Age and gender effects on serotonin-dependent plasticity in respiratory motor control

被引：72

作者：

Behan, M ^{[1
]}

Zabka, AG ^{[1
]}

Mitchell, GS ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Vet Med, Dept Comparat Biosci, Madison, WI 53706 USA

来源：

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY | 2002年 / 131卷 / 1-2期

关键词：

control of breathing; plasticity; development; age; hypoxia; long-term-facilitation; mammals; rat; seroton-independent; gender;

D O I：

10.1016/S1569-9048(02)00038-1

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

We review recent evidence indicating that serotonin-dependent plasticity in respiratory control is influenced by age and gender. Specifically, respiratory long-term-facilitation following intermittent hypoxia decreases with age in male rats, but increases in female rats. We speculate about a possible relationship between age and gender effects oil serotonin-dependent plasticity in upper airway motoneuron pools and the prevalence of obstructive sleep apnea. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：65 / 77

页数：13

共 125 条

[1] Long-term facilitation in obstructive sleep apnea patients during NREM sleep
Aboubakr, SE
Taylor, A
Ford, R
Siddiqi, S
Badr, MS
[J]. JOURNAL OF APPLIED PHYSIOLOGY, 2001, 91 (06) : 2751 - 2757
[2] Alves SE, 1998, J COMP NEUROL, V391, P322, DOI 10.1002/(SICI)1096-9861(19980216)391:3<322::AID-CNE3>3.3.CO
[3] 2-S
[4] SEROTONERGIC CELLS IN NUCLEUS RAPHE PALLIDUS PROVIDE TONIC DRIVE TO POSTERIOR CRICOARYTENOID MOTONEURONS VIA 5-HYDROXYTRYPTAMINE(2) RECEPTORS IN CATS
ARITA, H
ICHIKAWA, K
SAKAMOTO, M
[J]. NEUROSCIENCE LETTERS, 1995, 197 (02) : 113 - 116
[5] Babcock MA, 1998, SLEEP, V21, P709
[6] Bach KB, 2000, FASEB J, V14, pA77
[7] Hypoxia-induced long-term facilitation of respiratory activity is serotonin dependent
Bach, KB
Mitchell, GS
[J]. RESPIRATION PHYSIOLOGY, 1996, 104 (2-3): : 251 - 260
[8] Episodic but not continuous hypoxia elicits long-term facilitation of phrenic motor output in rats
Baker, TL
Mitchell, GS
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 2000, 529 (01): : 215 - 219
[9] New insights into the regulation and function of brain estrogen synthase (aromatase)
Balthazart, J
Ball, GF
[J]. TRENDS IN NEUROSCIENCES, 1998, 21 (06) : 243 - 249
[10] A review of central 5-HT receptors and their function
Barnes, NM
Sharp, T
[J]. NEUROPHARMACOLOGY, 1999, 38 (08) : 1083 - 1152

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