Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins

被引：205

作者：

Zhai, D. ^{[1
]}

Jin, C. ^{[1
]}

Satterthwait, A. C. ^{[1
]}

Reed, J. C. ^{[1
]}

机构：

[1] Burnham Inst Med Res, La Jolla, CA 92037 USA

来源：

CELL DEATH AND DIFFERENTIATION | 2006年 / 13卷 / 08期

关键词：

D O I：

10.1038/sj.cdd.4401937

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1419 / 1421

页数：3

共 20 条

[1] Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-XL
Becattini, B
Kitada, S
Leone, M
Monosov, E
Chandler, S
Zhai, DY
Kipps, TJ
Reed, JC
Pellecchia, M
[J]. CHEMISTRY & BIOLOGY, 2004, 11 (03): : 389 - 395
[2] Identification of chelerythrine as an inhibitor of BclXL function
Chan, SL
Lee, MC
Tan, KO
Yang, LK
Lee, ASY
Flotow, H
Fu, NY
Butler, MS
Soejarto, DD
Buss, AD
Yu, VC
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (23) : 20453 - 20456
[3] Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
Chen, L
Willis, SN
Wei, A
Smith, BJ
Fletcher, JI
Hinds, MG
Colman, PM
Day, CL
Adams, JM
Huang, DCS
[J]. MOLECULAR CELL, 2005, 17 (03) : 393 - 403
[4] Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands
Day, CL
Chen, L
Richardson, SJ
Harrison, PJ
Huang, DCS
Hinds, MG
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (06) : 4738 - 4744
[5] Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
Degterev, A
Lugovskoy, A
Cardone, M
Mulley, B
Wagner, G
Mitchison, T
Yuan, JY
[J]. NATURE CELL BIOLOGY, 2001, 3 (02) : 173 - 182
[6] Solution structure of human BCL-w - Modulation of ligand binding by the C-terminal helix
Denisov, AY
Madiraju, MSR
Chen, G
Khadir, A
Beauparlant, P
Attardo, G
Shore, GC
Gehring, K
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (23) : 21124 - 21128
[7] Bcl-2 family proteins as targets for anticancer drug design
Huang, ZW
[J]. ONCOGENE, 2000, 19 (56) : 6627 - 6631
[8] Discovery, characterization, and structure - Activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins
Kitada, S
Leone, M
Sareth, S
Zhai, DY
Reed, JC
Pellecchia, M
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 2003, 46 (20) : 4259 - 4264
[9] Dysregulation of apoptosis genes in hematopoietic malignancies
Kitada, S
Pedersen, IM
Schimmer, AD
Reed, JC
[J]. ONCOGENE, 2002, 21 (21) : 3459 - 3474
[10] Leone M, 2003, CANCER RES, V63, P8118

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