ML -: a conserved domain involved in innate immunity and lipid metabolism

被引：203

作者：

Inohara, N ^{[1
]}

Nuñez, G ^{[1
]}

机构：

[1] Univ Michigan, Sch Med, Dept Pathol & Comprehens Canc, Ann Arbor, MI 48109 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2002年 / 27卷 / 05期

关键词：

D O I：

10.1016/S0968-0004(02)02084-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ML (MD-2-related lipid-recognition) is a novel domain identified in MD-1, MD-2, GM2A, Npc2 and multiple proteins of unknown function in plants, animals and fungi. These single-domain proteins were predicted to form a P-rich fold containing multiple strands, and to mediate diverse biological functions through interacting with specific lipids.

引用

页码：219 / 221

页数：3

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