Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease

被引：13

作者：

Burt, RK ^{[1
]}

Brenner, M

Burns, W

Courier, E

Firestein, G

Hahn, B

Heslop, H

Link, C

McFarland, H

Roland, M

Territo, M

Tsokos, G

Traynor, A

机构：

[1] Northwestern Univ, Med Ctr, Chicago, IL 60611 USA

[2] Rupert H Lurie Canc Ctr, Chicago, IL 60611 USA

[3] Baylor Coll Med, Cell & Gene Therapy Ctr, Houston, TX 77030 USA

[4] Med Coll Wisconsin, Milwaukee, WI 53226 USA

[5] Univ Calif San Diego, San Diego, CA 92103 USA

[6] Univ Calif Los Angeles, Los Angeles, CA USA

[7] Human Gene Therapy Res Inst, Des Moines, IA USA

[8] NIH, Bethesda, MD 20892 USA

[9] Henry M Jackson Fdn Advancement Mil Sci, Rockville, MD USA

来源：

JOURNAL OF CLINICAL IMMUNOLOGY | 2000年 / 20卷 / 01期

关键词：

hematopoietic stem cell transplantation; gene-marked autologous stem cells; autoimmune disease;

D O I：

10.1023/A:1006673408343

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In phase I(safety) trials, we have demonstrated the feasibility of autologous hematopoietic stem cell transplantation (HSCT) for patients with autoimmune diseases. Although this review comments on results of our phase I trials, the focus is on phase II (efficacy) trials using gene-marked autologous stem cells.

引用

页码：1 / 9

页数：9

共 42 条

[1] Gene transfer to hematopoietic cells [J].

Brenner, MK .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (05) :337-339

[2] GENE MARKING TO DETERMINE WHETHER AUTOLOGOUS MARROW INFUSION RESTORES LONG-TERM HEMATOPOIESIS IN CANCER-PATIENTS [J].

BRENNER, MK ;

RILL, DR ;

HOLLADAY, MS ;

HESLOP, HE ;

MOEN, RC ;

BUSCHLE, M ;

KRANCE, RA ;

SANTANA, VM ;

ANDERSON, WF ;

IHLE, JN .

LANCET, 1993, 342 (8880) :1134-1137

[3]

Brooks PM, 1998, ARTHRITIS RHEUM, V41, pS132

[4]

Burt RK, 1998, BLOOD, V92, p324A

[5]

Burt RK, 1998, ARTHRITIS RHEUM, V41, pS241

[6]

Burt RK, 1999, ARTHRITIS RHEUM, V42, P2281, DOI 10.1002/1529-0131(199911)42:11<2281::AID-ANR4>3.0.CO

[7]

2-E

[8] T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients [J].

Burt, RK ;

Traynor, AE ;

Cohen, B ;

Karlin, KH ;

Davis, FA ;

Stefoski, D ;

Terry, C ;

Lobeck, L ;

Russell, EJ ;

Goolsby, C ;

Rosen, S ;

Gordon, LI ;

Keever-Taylor, C ;

Brush, M ;

Fishman, M ;

Burns, WH .

BONE MARROW TRANSPLANTATION, 1998, 21 (06) :537-541

[9] Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation [J].

Burt, RK ;

Traynor, AE ;

Pope, R ;

Schroeder, J ;

Cohen, B ;

Karlin, KH ;

Lobeck, L ;

Goolsby, C ;

Rowlings, P ;

Davis, FA ;

Stefoski, D ;

Terry, C ;

Keever-Taylor, C ;

Rosen, S ;

Vesole, D ;

Fishman, M ;

Brush, M ;

Mujias, S ;

Villa, M ;

Burns, WH .

BLOOD, 1998, 92 (10) :3505-3514

[10] Hematopoietic stem-cell transplantation for systemic lupus erythematosus [J].

Burt, RK ;

Traynor, A ;

RamseyGoldman, R .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (24) :1777-1778

← 1 2 3 4 5 →