Antibodies, killer toxins and antifungal immunoprotection: A lesson from nature

被引：60

作者：

Cassone, A ^{[1
]}

Conti, S ^{[1
]}

DeBernardis, F ^{[1
]}

Polonelli, L ^{[1
]}

机构：

[1] UNIV PARMA,INST MICROBIOL,I-43100 PARMA,ITALY

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 04期

关键词：

D O I：

10.1016/S0167-5699(97)84662-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cellular immunity is usually considered the principal defence mechanism against human opportunistic fungi. Recently, detection of protective antibodies has provoked a resurgence of interest in humoral immunity as critical to antifungal protection. In particular, the discovery of human natural fungicidal antibodies acting as internal images of yeast killer toxins has highlighted the importance of the idiotypic network and has suggested new immunotherapeutic approaches against fungal pathogens.

引用

页码：164 / 169

页数：6

共 31 条

[1] ALIOUAT EM, 1993, SERODIAGN IMMUNOTHER, V5, P102
[2] PRODUCTION AND FUNCTION OF CYTOKINES IN NATURAL AND ACQUIRED-IMMUNITY TO CANDIDA-ALBICANS INFECTION
ASHMAN, RB
PAPADIMITRIOU, JM
[J]. MICROBIOLOGICAL REVIEWS, 1995, 59 (04) : 646 - &
[3] ANTIBODY IMMUNITY AND INVASIVE FUNGAL-INFECTIONS
CASADEVALL, A
[J]. INFECTION AND IMMUNITY, 1995, 63 (11) : 4211 - 4218
[4] RATS CLEARING A VAGINAL INFECTION BY CANDIDA-ALBICANS ACQUIRE SPECIFIC, ANTIBODY-MEDIATED RESISTANCE TO VAGINAL REINFECTION
CASSONE, A
BOCCANERA, M
ADRIANI, D
SANTONI, G
DEBERNARDIS, F
[J]. INFECTION AND IMMUNITY, 1995, 63 (07) : 2619 - 2624
[5] MECHANISM AND REGULATION OF IMMUNOGLOBULIN ISOTYPE SWITCHING
COFFMAN, RL
LEBMAN, DA
ROTHMAN, P
[J]. ADVANCES IN IMMUNOLOGY, VOL 54, 1993, 54 : 229 - 270
[6] Fidel Paul L. Jr., 1994, Trends in Microbiology, V2, P202, DOI 10.1016/0966-842X(94)90112-I
[7] OPPORTUNISTIC CANDIDIASIS - AN EPIDEMIC OF THE 1980S
FISHERHOCH, SP
HUTWAGNER, L
[J]. CLINICAL INFECTIOUS DISEASES, 1995, 21 (04) : 897 - 904
[8] ANTIBODY-RESPONSE THAT PROTECTS AGAINST DISSEMINATED CANDIDIASIS
HAN, YM
CUTLER, JE
[J]. INFECTION AND IMMUNITY, 1995, 63 (07) : 2714 - 2719
[9] Therapeutic potential of antiidiotype single chain antibodies with yeast killer toxin activity
Magliani, W
Conti, S
DeBernardis, F
Gerloni, M
Bertolotti, D
Mozzoni, P
Cassone, A
Polonelli, L
[J]. NATURE BIOTECHNOLOGY, 1997, 15 (02) : 155 - 158
[10] THE ROLE OF HSP90 IN FUNGAL INFECTION
MATTHEWS, R
BURNIE, J
[J]. IMMUNOLOGY TODAY, 1992, 13 (09): : 345 - 348

← 1 2 3 4 →