Citrate-reduced silver hydrosol modified with ω-mercaptoalkanoic acids self-assembled monolayers as a substrate for surface-enhanced resonance Raman scattering.: A study with cytochrome c

被引：16

作者：

Bonifacio, A ^{[1
]}

van der Sneppen, L ^{[1
]}

Gooijer, C ^{[1
]}

van der Zwan, G ^{[1
]}

机构：

[1] Free Univ Amsterdam, Laser Ctr, Analyt Chem & Appl Spectroscopy, NL-1081 HV Amsterdam, Netherlands

来源：

LANGMUIR | 2004年 / 20卷 / 14期

关键词：

D O I：

10.1021/la049786v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new citrate-reduced silver hydrosol coated with omega-mercaptoalkanoic acids (mercaptopropionic and mercaptoundecanoic acids) self-assembled monolayers was prepared and characterized with surface-enhanced Raman spectroscopy. The structure and the quality of the coating monolayers are discussed and compared to similar coated and uncoated silver hydrosols previously developed. As an application, the new hydrosol was used as a biocompatible and efficient metal substrate for a surface-enhanced resonance Raman scattering (SERRS) study of cytochrome c. The high-quality SERRS spectra reported of cytochrome c (obtained using only 1 muL of a micromolar cytochrome solution) are discussed and compared with data available from literature studies.

引用

页码：5858 / 5864

页数：7

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[11] Electron transfer dynamics of cytochrome c bound to self-assembled monolayers on silver electrodes [J].