3D EXAFS refinement of the Cu site of azurin sheds light on the nature of structural change at the metal centre in an oxidation-reduction process: an integrated approach combining EXAFS and crystallography

被引：51

作者：

Cheung, KC

Strange, RW

Hasnain, SS ^{[1
]}

机构：

[1] De Montfort Univ, Fac Sci Appl, Leicester LE1 9BH, Leics, England

[2] CCLRC Daresbury Lab, Warrington WA4 4AD, Cheshire, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2000年 / 56卷

关键词：

D O I：

10.1107/S0907444900003310

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-dimensional information is obtained for the Cu site in azurin at very high resolution by combining high-resolution crystallographic structures and EXAFS data for the oxidized and reduced form of the protein. This combined approach has allowed us to define the subtle structural changes (<0.1 Angstrom) which take place at the Cu site during a single-electron redox process.

引用

页码：697 / 704

页数：8

共 44 条

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