学术探索
学术期刊
新闻热点
数据分析
智能评审

Relationship of viral infections to wheezing illnesses and asthma

被引：98
作者：
Gern, JE
Busse, WW
机构：
[1] Univ Wisconsin Hosp, Dept Pediat, Madison, WI 53792 USA
[2] Univ Wisconsin Hosp, Dept Med, Madison, WI 53792 USA
来源：
NATURE REVIEWS IMMUNOLOGY | 2002年 / 2卷 / 02期
关键词：
D O I：
10.1038/nri725
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Viral infections can influence both the development and the severity of asthma. In early life, viral infections can either increase or, remarkably, decrease the risk of subsequent asthma. In children and adults with existing asthma, viral respiratory infections frequently cause acute airway obstruction and wheezing. This article discusses the influence of viral infections on mechanisms of virus-induced airway inflammation in relationship to the development, persistence and severity of asthma.
引用
收藏
页码：132 / 138
页数：7
相关论文
共 82 条
  • [1] IL-8 and neutrophil elastase levels in the respiratory tract of infants with RSV bronchiolitis
    Abu-Harb, M
    Bell, F
    Finn, A
    Rao, WH
    Nixon, L
    Shale, D
    Everard, ML
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1999, 14 (01) : 139 - 143
  • [2] LOCALIZATION OF HUMAN RHINOVIRUS REPLICATION IN THE UPPER RESPIRATORY-TRACT BY IN-SITU HYBRIDIZATION
    ARRUDA, E
    BOYLE, TR
    WINTHER, B
    PEVEAR, DC
    GWALTNEY, JM
    HAYDEN, FG
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1995, 171 (05) : 1329 - 1333
  • [3] Respiratory tract viral infections in inner-city asthmatic adults
    Atmar, RL
    Guy, E
    Guntupalli, KK
    Zimmerman, JL
    Bandi, VD
    Baxter, BD
    Greenberg, SB
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1998, 158 (22) : 2453 - 2459
  • [4] Siblings, day-care attendance, and the risk of asthma and wheezing during childhood
    Ball, TM
    Castro-Rodriguez, JA
    Griffith, KA
    Holberg, CJ
    Martinez, FD
    Wright, AL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (08) : 538 - 543
  • [5] Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study
    Bont, L
    Heijnen, CJ
    Kavelaars, A
    van Aalderen, WMC
    Brus, F
    Draaisma, JTM
    Geelen, SM
    Kimpen, JLL
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 161 (05) : 1518 - 1523
  • [6] BRUNETTE MG, 1988, PEDIATRICS, V81, P624
  • [7] Advances in immunology - Asthma
    Busse, WW
    Lemanske, RF
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (05) : 350 - 362
  • [8] A COMMON COLD VIRUS, RHINOVIRUS-16, POTENTIATES AIRWAY INFLAMMATION AFTER SEGMENTAL ANTIGEN BRONCHOPROVOCATION IN ALLERGIC SUBJECTS
    CALHOUN, WJ
    DICK, EC
    SCHWARTZ, LB
    BUSSE, WW
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1994, 94 (06) : 2200 - 2208
  • [9] LTB4-induced nasal gland serous cell secretion mediated by neutrophil elastase
    Cardell, LO
    Agustí, C
    Takeyama, K
    Stjärne, P
    Nadel, JA
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 160 (02) : 411 - 414
  • [10] Oxidant tone regulates RANTES gene expression in airway epithelial cells infected with respiratory syncytial virus - Role in viral-induced interferon regulatory factor activation
    Casola, A
    Burger, N
    Liu, TS
    Jamaluddin, M
    Brasier, AR
    Garofalo, RP
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (23) : 19715 - 19722
123456789