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Relationship of viral infections to wheezing illnesses and asthma

被引：98
作者：
Gern, JE
Busse, WW
机构：
[1] Univ Wisconsin Hosp, Dept Pediat, Madison, WI 53792 USA
[2] Univ Wisconsin Hosp, Dept Med, Madison, WI 53792 USA
来源：
NATURE REVIEWS IMMUNOLOGY | 2002年 / 2卷 / 02期
关键词：
D O I：
10.1038/nri725
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Viral infections can influence both the development and the severity of asthma. In early life, viral infections can either increase or, remarkably, decrease the risk of subsequent asthma. In children and adults with existing asthma, viral respiratory infections frequently cause acute airway obstruction and wheezing. This article discusses the influence of viral infections on mechanisms of virus-induced airway inflammation in relationship to the development, persistence and severity of asthma.
引用
收藏
页码：132 / 138
页数：7
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