How does DNA sequence motif discovery work?

被引:67
作者
D'haeseleer, Patrik [1 ]
机构
[1] Lawrence Livermore Natl Lab, Microbial Syst Div, Biosci Directorate, Livermore, CA 94551 USA
关键词
D O I
10.1038/nbt0806-959
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
How can we computationally extract an unknown motif from a set of target sequences? What are the principles behind the major motif discovery algorithms? Which of these should we use, and how do we know we've found a 'real' motif?.
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页码:959 / 961
页数:3
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