A high-density single-nucleotide polymorphism map of Xq25-q28

被引:13
作者
Taillon-Miller, P [1 ]
Kwok, PY [1 ]
机构
[1] Washington Univ, Sch Med, Div Dermatol, St Louis, MO 63110 USA
关键词
D O I
10.1006/geno.2000.6165
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A high-density single-nucleotide polymorphism (SNP) map was developed for Xq25-q28 using a targeted approach to SNP discovery. This high-density map includes 217 new SNP markers, and 117 are informative in the CEPH parent population with >20% minor allele frequency. The average distance between SNP markers is 100 kb in the targeted regions. This is the densest genetic map of Xq25-q28 to date. The SNP markers are presented in order by their distance in megabases along the X chromosome, and the markers from the current genetic map are placed using the same scale to produce an integrated map of the region. (C) 2000 Academic Press.
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收藏
页码:195 / 202
页数:8
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