A high-density single-nucleotide polymorphism map of Xq25-q28

被引：13

作者：

Taillon-Miller, P ^{[1
]}

Kwok, PY ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Div Dermatol, St Louis, MO 63110 USA

来源：

GENOMICS | 2000年 / 65卷 / 03期

关键词：

D O I：

10.1006/geno.2000.6165

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A high-density single-nucleotide polymorphism (SNP) map was developed for Xq25-q28 using a targeted approach to SNP discovery. This high-density map includes 217 new SNP markers, and 117 are informative in the CEPH parent population with >20% minor allele frequency. The average distance between SNP markers is 100 kb in the targeted regions. This is the densest genetic map of Xq25-q28 to date. The SNP markers are presented in order by their distance in megabases along the X chromosome, and the markers from the current genetic map are placed using the same scale to produce an integrated map of the region. (C) 2000 Academic Press.

引用

页码：195 / 202

页数：8