Imaging and Biomarkers in Early Alzheimer's Disease and Mild Cognitive Impairment

被引：34

作者：

Petersen, R. C. ^{[1
]}

Jack, C. R., Jr. ^{[2
]}

机构：

[1] Mayo Clin, Coll Med, Dept Neurol, Rochester, MN 55905 USA

[2] Mayo Clin, Coll Med, Dept Radiol, Div Neuroradiol, Rochester, MN USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2009年 / 86卷 / 04期

关键词：

PUBLIC-HEALTH IMPACT; CEREBROSPINAL-FLUID; CSF BIOMARKERS; MRI; DIAGNOSIS; PROGRESSION; PREDICTION; DEMENTIA; VOLUME; PIB;

D O I：

10.1038/clpt.2009.166

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A major focus of research on aging and dementia pertains to the prediction of future cognitive decline. Toward this end, several longitudinal studies are under way that are designed to explore early predictors of cognitive impairment. Neuroimaging techniques and biomarkers have shown promise in this application. Ultimately, it is likely that the use of a combination of neuroimaging and chemical biomarkers will be involved in predicting the development of dementia and Alzheimer's disease (AD).

引用

页码：438 / 441

页数：4

共 29 条

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