Recommendations for the management of herpes zoster

被引:507
作者
Dworkin, Robert H.
Johnson, Robert W.
Breuer, Judith
Gnann, John W.
Levin, Myron J.
Backonja, Miroslav
Betts, Robert F.
Gershon, Anne A.
Haanpaa, Maija L.
McKendrick, Michael W.
Nurmikko, Turo J.
Oaklander, Anne Louise
Oxman, Michael N.
Pavan-Langston, Deborah
Petersen, Karin L.
Rowbotham, Michael C.
Schmader, Kenneth E.
Stacey, Brett R.
Tyring, Stephen K.
van Wijck, Albert J. M.
Wallace, Mark S.
Wassilew, Sawko W.
Whitley, Richard J.
机构
[1] Univ Rochester, Sch Med & Dent, Dept Anesthesiol, Rochester, NY 14642 USA
[2] Univ Rochester, Dept Neurol, Rochester, NY 14642 USA
[3] Univ Rochester, Dept Med, Rochester, NY 14642 USA
[4] Columbia Univ, Dept Pediat, New York, NY USA
[5] Univ Alabama Birmingham, Dept Med, Birmingham, AL USA
[6] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL USA
[7] Birmingham Vet Affairs Med Ctr, Birmingham, AL USA
[8] Univ Colorado, Dept Pediat, Denver, CO 80202 USA
[9] Univ Wisconsin, Dept Neurol, Madison, WI 53706 USA
[10] Harvard Univ, Dept Neurol, Cambridge, MA 02138 USA
[11] Harvard Univ, Sch Med, Dept Ophthalmol, Boston, MA USA
[12] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA
[13] Univ Calif San Diego, Dept Anesthesiol, San Diego, CA 92103 USA
[14] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[15] Duke Univ, Dept Med, Durham, NC USA
[16] Univ Texas, Hlth Sci Ctr, Houston, TX USA
[17] Univ Oregon, Dept Anesthesiol, Portland, OR USA
[18] Univ Bristol, Dept Anesthesiol, Bristol, Avon, England
[19] Queen Mary Coll, Skin Virus Lab, London, England
[20] Royal Hallamshire Hosp, Dept Infect & Trop Med, Sheffield S10 2JF, S Yorkshire, England
[21] Univ Liverpool, Dept Neurol Sci, Liverpool, Merseyside, England
[22] Helsinki Univ Hosp, Dept Anesthesiol & Intens Care, Helsinki, Finland
[23] Helsinki Univ Hosp, Dept Neurol, Helsinki, Finland
[24] Univ Utrecht, Pain Clin, Utrecht, Netherlands
[25] Klinikum Krefeld, Dermatol Klin, Krefeld, Germany
关键词
D O I
10.1086/510206
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.
引用
收藏
页码:S1 / S26
页数:26
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