Betulinans A and B, two benzoquinone compounds from Lenzites betulina

被引：64

作者：

Lee, IK

Yun, BS

Cho, SM

Kim, WG

Kim, JP

Ryoo, IJ

Koshino, H

Yoo, ID

机构：

[1] KOREA ADV INST SCI & TECHNOL,KOREA RES INST BIOSCI & BIOTECHNOL,TAEJON 305600,SOUTH KOREA

[2] RIKEN,WAKO,SAITAMA 35101,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 11期

关键词：

D O I：

10.1021/np960253z

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two lipid peroxidation inhibitors, designated as betulinans A (1) and B (2), were isolated from the MeOH extract of Lenzites betulina. The structures of these compounds have been determined to be 2,5-diphenyl-3,6-dimethoxy-p-benzoquinone and 2-phenyl-3-methoxy-[1H-2-benzopyran][4,3-e][p]benzoquinone, respectively, on the basis of various spectral data. Betulinans A and B inhibited lipid peroxidation with IC50 values of 0.46 and 2.88 mu g/mL, respectively.

引用

收藏

页码：1090 / 1092

页数：3

相关论文

共 15 条

[1] OXIDATIVE STRESS, GLUTAMATE, AND NEURODEGENERATIVE DISORDERS [J].

COYLE, JT ;

PUTTFARCKEN, P .

SCIENCE, 1993, 262 (5134) :689-695

[2]

DIVEKAR PV, 1954, CAN J CHEM, V37, P1970

[3] FUNGUS PIGMENTS .10. THE ULTRA-VIOLET ABSORPTION OF SOME SUBSTITUTED 2,5-DIPHENYLBENZOQUINONES AND THEIR LEUCOACETATES [J].

GRIPENBERG, J .

ACTA CHEMICA SCANDINAVICA, 1958, 12 (09) :1762-1767

[4]

HALLIWELL B, 1989, FREE RADICAL BIO MED, P416

[5] OXYGEN RADICALS IN THE ADULT RESPIRATORY-DISTRESS SYNDROME, IN MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY, AND IN CEREBRAL VASCULAR DAMAGE [J].

HAMMOND, B ;

KONTOS, HA ;

HESS, ML .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1985, 63 (03) :173-187

[6]

Imazeki R, 1989, COLORED ILLUSTRATION, V2, P159

[7] ISOLATION OF POLYPORIC ACID FROM LOPHARIA PAPYRACEA [J].

JIRAWONGSE, V ;

RAMSTAD, E ;

WOLINSKY, J .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1962, 51 (11) :1108-&

[8] STUDIES ON FREE-RADICAL SCAVENGING SUBSTANCES FROM MICROORGANISMS .1. CARAZOSTATIN, A NEW FREE-RADICAL SCAVENGER PRODUCED BY STREPTOMYCES-CHROMOFUSCUS DC-118 [J].

KATO, S ;

KAWAI, H ;

KAWASAKI, T ;

TODA, Y ;

URATA, T ;

HAYAKAWA, Y .

JOURNAL OF ANTIBIOTICS, 1989, 42 (12) :1879-1881

[9] PYRROLOSTATIN, A NOVEL LIPID-PEROXIDATION INHIBITOR FROM STREPTOMYCES-CHRESTOMYCETICUS - TAXONOMY, FERMENTATION, ISOLATION, STRUCTURE ELUCIDATION AND BIOLOGICAL PROPERTIES [J].

KATO, S ;

SHINDO, K ;

KAWAI, H ;

ODAGAWA, A ;

MATSUOKA, M ;

MOCHIZUKI, J .

JOURNAL OF ANTIBIOTICS, 1993, 46 (06) :892-899

[10] STRUCTURE OF BASIDIOMYCETE ORTHO QUINONE PHLEBIARUBRONE AND OF ITS NOVEL ACETYLATION PRODUCT [J].

MCMORRIS, TC ;

ANCHEL, M .

TETRAHEDRON, 1967, 23 (10) :3985-&