Simultaneous optimization of the analysis time and the concentration detectability in open-tubular liquid chromatography

被引：17

作者：

Desmet, G ^{[1
]}

Baron, GV ^{[1
]}

机构：

[1] Free Univ Brussels, Dept Chem Engn, B-1050 Brussels, Belgium

来源：

JOURNAL OF CHROMATOGRAPHY A | 2000年 / 867卷 / 1-2期

关键词：

optimization; analysis time; concentration detectability;

D O I：

10.1016/S0021-9673(99)01102-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Scott's OT-LC minimal analysis time problem has been solved analytically and has been extended to thick-film and/or large diameter columns. The optimisation analysis has also been applied to a number of relative performance indexes (C-max/t(anal), C-max.d/t(anal) and C-max.u.d(2)/t(anal)) which provide a quantitative insight on the extent to which OT-LC allows to combine short analysis times with a large concentration detectability. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：23 / 43

页数：21

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