High production of hyaluronic and lactic acids by Streptococcus zooepidemicus in fed-batch culture using commercial and marine peptones from fishing by-products

被引:38
作者
Antonio Vazquez, Jose [1 ]
Montemayor, Maria I. [1 ]
Fraguas, Javier [1 ,2 ]
Anxo Murado, Miguel [1 ]
机构
[1] Inst Invest Marinas Punta Betin, Grp Reciclado & Valorizac Mat Residuales, CSIC, Vigo 36208, Galicia, Spain
[2] Dilsea SL Porto Pesqueiro Vigo, Vigo 36202, Galicia, Spain
关键词
Streptococcus zooepidemicus; Hyaluronic acid; Lactic acid; Marine peptones; Logistic equation; PEDIOCIN PRODUCTION; NITROGEN-SOURCES; URONIC-ACIDS; BACTERIA; GROWTH; VISCERA; NISIN; FERMENTATION; HYDROLYSIS; MEDIA;
D O I
10.1016/j.bej.2008.11.007
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
The combined production of biomass, hyaluronic acid (HA) and lactic acid (LA) in a glucose fed-batch system was studied. The complex culture media used were formulated with commercial and residual peptones from fish by-products. In all cases, fed-batch fermentations increased the productive period of HA and LA. Tryptone led to the highest productions but with the peptones from shark by-products similar LA concentrations and prominent HA levels were reached. Moreover, with this residual peptone higher molecular weight of HA were achieved. On the other hand, the equations proposed adjusted with accuracy and high statistical robustness the experimental kinetic profiles. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:125 / 130
页数:6
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