All-electrical switching and control mechanism for actomyosin-powered nanoactuators

被引:38
作者
Mihajlovic, G [1 ]
Brunet, NM
Trbovic, J
Xiong, P
von Molnár, S
Chase, PB
机构
[1] Florida State Univ, MARTECH, Tallahassee, FL 32306 USA
[2] Florida State Univ, Dept Phys, Tallahassee, FL 32306 USA
[3] Florida State Univ, Dept Biol Sci, Tallahassee, FL 32306 USA
[4] Florida State Univ, Program Mol Biophys, Tallahassee, FL 32306 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
D O I
10.1063/1.1777815
中图分类号
O59 [应用物理学];
学科分类号
摘要
A fast all-electrical activation and control mechanism for biomolecular motor-powered nanoactuators has been developed. Rapid and reversible on-off control of actomyosin biomolecular motors was experimentally demonstrated using in vitro motility assays. The results show that the motility of the actin filaments can be cycled repeatedly by electrically controlled thermal activation in the temperature range from 10degreesC to 50degreesC without functional loss. The fast response of the filaments upon rapid temperature switching suggests that thermal activation provides an effective method for turning actomyosin-powered nanoactuators on and off. (C) 2004 American Institute of Physics.
引用
收藏
页码:1060 / 1062
页数:3
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