Assembly of kinetochores in vertebrate cells

被引：40

作者：

Fukagawa, T ^{[1
]}

机构：

[1] Natl Inst Genet, Japan Sci & Technol Agcy, JST, PRESTO, Mishima, Shizuoka 4118540, Japan

[2] Grad Univ Adv Studies, Mishima, Shizuoka 4118540, Japan

来源：

EXPERIMENTAL CELL RESEARCH | 2004年 / 296卷 / 01期

基金：

日本科学技术振兴机构;

关键词：

centromere; kinetochores; vertebrate cells;

D O I：

10.1016/j.yexcr.2004.03.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The centromere is a specialized region of each chromosome that is essential for faithful chromosome segregation during mitosis and meiosis in eukaryotic cells. Centromeres are the site at which kinetochores are formed. The kinetochore is responsible for microtubule binding and chromosome movement. In this review, I will focus on recent advances in our understanding of centromere DNAs as sites for kinetochore assembly and the mechanism underlying kinetochore assembly in vertebrate cells. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：21 / 27

页数：7

共 60 条

[31] Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2 [J].

Martin-Lluesma, S ;

Stucke, VM ;

Nigg, EA .

SCIENCE, 2002, 297 (5590) :2267-2270

[32] A HUMAN CENTROMERE ANTIGEN (CENP-B) INTERACTS WITH A SHORT SPECIFIC SEQUENCE IN ALPHOID DNA, A HUMAN CENTROMERIC SATELLITE [J].

MASUMOTO, H ;

MASUKATA, H ;

MURO, Y ;

NOZAKI, N ;

OKAZAKI, T .

JOURNAL OF CELL BIOLOGY, 1989, 109 (05) :1963-1973

[33] Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore [J].

Measday, V ;

Hailey, DW ;

Pot, I ;

Givan, SA ;

Hyland, KM ;

Cagney, G ;

Fields, S ;

Davis, TN ;

Hieter, P .

GENES & DEVELOPMENT, 2002, 16 (01) :101-113

[34] Stretching it: putting the CEN(P-A) in centromere [J].

Mellone, BG ;

Allshire, RC .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2003, 13 (02) :191-198

[35] EVIDENCE THAT THE MIF2 GENE OF SACCHAROMYCES-CEREVISIAE ENCODES A CENTROMERE PROTEIN WITH HOMOLOGY TO THE MAMMALIAN CENTROMERE PROTEIN CENP-C [J].

MELUH, PB ;

KOSHLAND, D .

MOLECULAR BIOLOGY OF THE CELL, 1995, 6 (07) :793-807

[36] AUTOANTIBODY TO CENTROMERE (KINETOCHORE) IN SCLERODERMA SERA [J].

MOROI, Y ;

PEEBLES, C ;

FRITZLER, MJ ;

STEIGERWALD, J ;

TAN, EM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (03) :1627-1631

[37] CENP-I is essential for centromere function in vertebrate cells [J].

Nishihashi, A ;

Haraguchi, T ;

Hiraoka, Y ;

Ikemura, T ;

Regnier, V ;

Dodson, H ;

Earnshaw, WC ;

Fukagawa, T .

DEVELOPMENTAL CELL, 2002, 2 (04) :463-476

[38] CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA [J].

Ohzeki, J ;

Nakano, M ;

Okada, T ;

Masumoto, H .

JOURNAL OF CELL BIOLOGY, 2002, 159 (05) :765-775

[39] A 17-KD CENTROMERE PROTEIN (CENP-A) COPURIFIES WITH NUCLEOSOME CORE PARTICLES AND WITH HISTONES [J].

PALMER, DK ;

ODAY, K ;

WENER, MH ;

ANDREWS, BS ;

MARGOLIS, RL .

JOURNAL OF CELL BIOLOGY, 1987, 104 (04) :805-815

[40] cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site [J].

Partridge, JF ;

Scott, KSC ;

Bannister, AJ ;

Kouzarides, T ;

Allshire, RC .

CURRENT BIOLOGY, 2002, 12 (19) :1652-1660

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