Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium

被引:33
作者
Huang, Yong [1 ,2 ]
Zhang, Honglei [3 ]
Qiao, Haixia [1 ]
Nian, Xiaofeng [1 ]
Zhang, Xuejiao [1 ]
Wang, Wendong [1 ]
Zhang, Xiaoyun [1 ]
Chang, Xiaotong [1 ]
Han, Shuguang [2 ]
Pang, Xiaofeng [2 ,4 ]
机构
[1] Hebei North Univ, Coll Lab Med, Zhangjiakou 075000, Peoples R China
[2] Univ Elect Sci & Technol China, Inst Life Sci & Technol, Chengdu 610054, Peoples R China
[3] Hebei Univ, Coll Chem Environm Sci, Baoding 071000, Peoples R China
[4] Chinese Acad Sci, Int Ctr Mat Phys, Shenyang 110015, Peoples R China
关键词
Calcium silicate; Zinc; Hydroxyapatite; Anticorrosion; Cytocompatibility; CORROSION-RESISTANCE; SUBSTITUTED HYDROXYAPATITE; CARBON/CARBON COMPOSITES; ELECTRODEPOSITION METHOD; ANTIBACTERIAL PROPERTIES; BIOMEDICAL APPLICATIONS; ORTHOPEDIC APPLICATIONS; IMPLANT APPLICATIONS; PHOSPHATE; BIOACTIVITY;
D O I
10.1016/j.apsusc.2015.10.034
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070305 [高分子化学与物理];
摘要
This work elucidated the corrosion resistance and cytocompatibility of electroplated Zn- and Si-containing bioactive calcium silicate/zinc-doped hydroxyapatite (ZnHA/CS) ceramic coatings on commercially pure titanium (CP-Ti). The formation of ZnHA/CS coating was investigated through Fourier transform infrared spectroscopy, X-ray diffraction (XRD), scanning electron microscopy, energy dispersive X-ray and inductively coupled plasma analyses. The XRD image showed that the reaction layer was mainly composed of HA and CaSiO3. The fabricated ZnHA/CS coatings presented a porous structure and appropriate thickness for possible applications in orthopaedic surgery. Potentiodynamic polarization tests showed that ZnHA/CS coatings exhibited higher corrosion resistance than CP-Ti. Dissolution tests on the coating also revealed that Si4+ and Zn2+ were leached at low levels. Moreover, MC3T3-E1 cells cultured on ZnHA/CS featured improved cell morphology, adhesion, spreading, proliferation and expression of alkaline phosphatase than those cultured on HA. The high cytocompatibility of ZnHA/CS could be mainly attributed to the combination of micro-porous surface effects and ion release (Zn2+ and Si4+). All these results indicate that ZnHA/CS composite-coated CP-Ti may be a potential material for orthopaedic applications. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:1776 / 1784
页数:9
相关论文
共 45 条
[1]
Bowers K T, 1992, Int J Oral Maxillofac Implants, V7, P302
[2]
Investigation on bioactivity, biocompatibility, thermal behavior and antibacterial properties of calcium silicate glass coatings containing Ag [J].
Catauro, M. ;
Bollino, F. ;
Papale, F. ;
Ciprioti, S. Vecchio .
JOURNAL OF NON-CRYSTALLINE SOLIDS, 2015, 422 :16-22
[3]
Nutrient element-based bioceramic coatings on titanium alloy stimulating osteogenesis by inducing beneficial osteoimmmunomodulation [J].
Chen, Zetao ;
Yi, Deliang ;
Zheng, Xuebin ;
Chang, Jiang ;
Wu, Chengtie ;
Xiao, Yin .
JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (36) :6030-6043
[4]
Surface microstructure and cell compatibility of calcium silicate and calcium phosphate composite coatings on Mg-Zn-Mn-Ca alloys for biomedical application [J].
Du, Hui ;
Wei, Zunjie ;
Wang, Hongwei ;
Zhang, Erlin ;
Zuo, Lin ;
Du, Lianping .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2011, 83 (01) :96-102
[5]
RETRACTED: Single walled carbon nanotubes reinforced mineralized hydroxyapatite composite coatings on titanium for improved biocompatible implant applications (Retracted Article) [J].
Gopi, D. ;
Shinyjoy, E. ;
Karthika, A. ;
Nithiya, S. ;
Kavitha, L. ;
Rajeswari, D. ;
Tang, Tingting .
RSC ADVANCES, 2015, 5 (46) :36766-36778
[6]
RETRACTED: Ball flower like manganese, strontium substituted hydroxyapatite/cerium oxide dual coatings on the AZ91 Mg alloy with improved bioactive and corrosion resistance properties for implant applications (Retracted Article) [J].
Gopi, D. ;
Murugan, N. ;
Ramya, S. ;
Shinyjoy, E. ;
Kavitha, L. .
RSC ADVANCES, 2015, 5 (35) :27402-27411
[7]
Influence of ionic substitution in improving the biological property of carbon nanotubes reinforced hydroxyapatite composite coating on titanium for orthopedic applications [J].
Gopi, D. ;
Shinyjoy, E. ;
Kavitha, L. .
CERAMICS INTERNATIONAL, 2015, 41 (04) :5454-5463
[8]
RETRACTED: Investigation on corrosion protection and mechanical performance of minerals substituted hydroxyapatite coating on HELCDEB-treated titanium using pulsed electrodeposition method (Retracted Article) [J].
Gopi, D. ;
Karthika, A. ;
Rajeswari, D. ;
Kavitha, L. ;
Pramod, R. ;
Dwivedi, Jishnu .
RSC ADVANCES, 2014, 4 (66) :34751-34759
[9]
RETRACTED: Electrodeposition of a porous strontium-substituted hydroxyapatite/zinc oxide duplex layer on AZ91 magnesium alloy for orthopedic applications (Retracted article. See MAR, 2023) [J].
Gopi, D. ;
Murugan, N. ;
Ramya, S. ;
Kavitha, L. .
JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (34) :5531-5540
[10]
Labile Zn ions on octacalcium phosphate-derived Zn-containing hydroxyapatite surfaces [J].
Honda, Yoshitomo ;
Anada, Takahisa ;
Morimoto, Shinji ;
Suzuki, Osamu .
APPLIED SURFACE SCIENCE, 2013, 273 :343-348