Mechanisms of resistance to quinupristin-dalfopristin among isolates of Enterococcus faecium from animals, raw meat, and hospital patients in western Europe

被引：111

作者：

Soltani, M

Beighton, D

Philpott-Howard, J

Woodford, N

机构：

[1] ARMRL, CPHL, London NW9 5HT, England

[2] Guys Kings & St Thomas Sch Dent, London SE5 9RW, England

[3] Guys Kings & St Thomas Sch Med, Publ Hlth Lab, London SE5 9PJ, England

[4] Guys Kings & St Thomas Sch Med, Dept Med Microbiol, London SE5 9PJ, England

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 02期

关键词：

D O I：

10.1128/AAC.44.2.433-436.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Twenty-eight quinupristin-dalfopristin-resistant isolates of Enterococcus faecium from hospital patients and nonhuman sources in European countries were studied. High-level resistance (MICs, greater than or equal to 32 mu g/ml) was associated with the presence of vat(E) (satG) (14 isolates [50%]) or vat(D) (satA) (6 isolates [21%]). These genes were not detected in eight (29%) isolates with lower levels of quinupristin-dalfopristin resistance (MICs, 4 to 16 mu g/ml). This suggests the presence of further mechanisms of resistance to quinupristin-dalfopristin in E. faecium.

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页码：433 / 436

页数：4

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