Indolizidine and quinolizidine alkaloids

被引：149

作者：

Michael, JP ^{[1
]}

机构：

[1] Univ Witwatersrand, Inst Mol Sci, Sch Chem, ZA-2050 Johannesburg, South Africa

来源：

NATURAL PRODUCT REPORTS | 2004年 / 21卷 / 05期

关键词：

D O I：

10.1039/b310689f

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review covers the isolation, structure determination, synthesis, chemical transformations and biological activity of indolizidine and quinolizidine alkaloids from microbial, plant and animal sources. Included in the review are the hydroxylated indolizidines lentiginosine, swainsonine, castanospermine and their analogues; alkaloids from animal sources, including ants, amphibians and beetles; ipalbidine, phenanthroindolizidines and related alkaloids; Lycopodium alkaloids; lupine alkaloids; and alkaloids from bacterial and marine sources. The literature from July 2002 to June 2003 is reviewed, and 174 references are cited.

引用

页码：625 / 649

页数：25

共 188 条

[1] Enantioselective synthesis of clavepictine analogues and evaluation of their cytotoxic activity [J].

Agami, C ;

Couty, F ;

Evano, G ;

Darro, F ;

Kiss, R .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 2003 (11) :2062-2070

[2] ENANTIOSELECTIVE TOTAL SYNTHESIS OF (-)-INDOLIZIDINES 209B AND 209D VIA A HIGHLY EFFICIENT AZA-[2,3]-WITTIG REARRANGEMENT OF VINYLAZIRIDINES [J].

AHMAN, J ;

SOMFAI, P .

TETRAHEDRON, 1995, 51 (35) :9747-9756

[3] The triclinic polymorph of dibromo[(-)-sparteine-κ2N,N′]zinc(II) [J].

Alcántara-Flores, JL ;

Bernès, S ;

Reyes-Ortega, Y ;

Zamorano-Ulloa, R .

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2003, 59 :M79-M81

[4] Enantioselective addition of organolithium reagents on isoquinoline [J].

Alexakis, A ;

Amiot, F .

TETRAHEDRON-ASYMMETRY, 2002, 13 (19) :2117-2122

[5] Enantioselective synthesis of piperidine, indolizidine, and quinolizidine alkaloids from a phenylglycinol-derived δ-lactam [J].

Amat, M ;

Llor, N ;

Hidalgo, J ;

Escolano, C ;

Bosch, J .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (05) :1919-1928

[6] Diastereoselective addition of chlorotitanium enolate of N-acyl thiazolidinethione to O-methyl oximes:: A novel, stereoselective synthesis of α,β-disubstituted β-amino carbonyl compounds via chiral auxiliary mediated azetine formation [J].

Ambhaikar, NB ;

Snyder, JP ;

Liotta, DC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (13) :3690-3691

[7] Convergent approach to pumiliotoxin alkaloids. Asymmetric total synthesis of (+)-pumiliotoxins A, B, and 225F [J].

Aoyagi, S ;

Hirashima, S ;

Saito, K ;

Kibayashi, C .

JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (16) :5517-5526

[8] Preparation of diamines by lithiation-substitution of imidazolidines and pyrimidines [J].

Ashweek, NJ ;

Coldham, I ;

Haxell, TFN ;

Howard, S .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2003, 1 (09) :1532-1544

[9] Concise asymmetric syntheses of (-)-lentiginosine and of its pyrrolizidinic analogue [J].

Ayad, T ;

Génisson, Y ;

Baltas, M ;

Gorrichon, L .

CHEMICAL COMMUNICATIONS, 2003, (05) :582-583

[10]

Ayad T, 2001, SYNLETT, P866

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