Eph family functions from an evolutionary perspective

被引：65

作者：

Drescher, U ^{[1
]}

机构：

[1] Kings Coll London, MRC, Ctr Dev Neurobiol, London SE1 1UL, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2002年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0959-437X(02)00316-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Eph receptor tyrosine kinases and ephrins have been identified in organisms ranging from sponges to flies and worms to chick, mice and humans, thus allowing their function to be approached also from an evolutionary perspective. The structural analysis of Eph/ephrin crystals is providing hints for the existence of Eph and ephrin folds in plants and suggests a mechanism for triggering bi-directional signalling.

引用

页码：397 / 402

页数：6

共 63 条

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