Nitrous oxide myelopathy in an abuser of whipped cream bulbs

被引:46
作者
Butzkueven, H [1 ]
King, JO [1 ]
机构
[1] Royal Melbourne Hosp, Melbourne, Vic, Australia
关键词
nitrous oxide toxicity; myelopathic disorders; substance abuse; anaesthetic toxicity;
D O I
10.1054/jocn.1998.0149
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 23 year old man presented with a severe posterior column myelopathy related to prolonged nitrous oxide abuse obtained from whipped cream bulbs. The site of pathology was identified by magnetic resonance imaging (MRI) and somatosensory evoked potentials. The mechanism of toxicity involves inactivation of vitamin B-12 dependent enzymes. Appropriate treatment with methionine and vitamin B-12 was instituted quickly with good neurological outcome. There are major concerns regarding the availability of nitrous oxide in supermarkets. (C) 2000 Harcourt Publishers Ltd.
引用
收藏
页码:73 / 75
页数:3
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