PANDIT: an evolution-centric database of protein and associated nucleotide domains with inferred trees

被引：50

作者：

Whelan, Simon

de Bakker, Paul I. W.

Quevillon, Emmanuel

Rodriguez, Nicolas

Goldman, Nick

机构：

[1] EMBL European Bioinformat Inst, Hinxton CB10 1SD, Cambs, England

[2] Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkj087

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

PANDIT is a database of homologous sequence alignments accompanied by estimates of their corresponding phylogenetic trees. It provides a valuable resource to those studying phylogenetic methodology and the evolution of coding-DNA and protein sequences. Currently in version 17.0, PANDIT comprises 7738 families of homologous protein domains; for each family, DNA and corresponding amino acid sequence multiple alignments are available together with high quality phylogenetic tree estimates. Recent improvements include expanded methods for phylogenetic tree inference, assessment of alignment quality and a redesigned web interface, available at the URL http://www.ebi.ac.uk/goldman-srv/pandit.

引用

收藏

页码：D327 / D331

页数：5

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