Modulating the outer membrane with small RNAs

被引:180
作者
Guillier, Maude
Gottesman, Susan
Storz, Gisela
机构
[1] NCI, Mol Biol Lab, Bethesda, MD 20892 USA
[2] NICHHD, Cell Biol & Metab Branch, Bethesda, MD 20892 USA
关键词
Hfq; OmpC; OmpA; sigma(E); OmpR;
D O I
10.1101/gad.1457506
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
MicF, one of the first chromosomally encoded regulatory small RNAs (sRNAs) to be discovered, was found to modulate the expression of OmpF, an abundant outer membrane protein. Several recent papers have now shown that this is not an isolated case. At least five other sRNAs also regulate the synthesis of outer membrane porins, and additional sRNAs modulate the expression of other outer membrane proteins. Here we review what is known about these sRNAs and discuss the implications of this regulation.
引用
收藏
页码:2338 / 2348
页数:11
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