Modulating the outer membrane with small RNAs

被引：180

作者：

Guillier, Maude

Gottesman, Susan

Storz, Gisela

机构：

[1] NCI, Mol Biol Lab, Bethesda, MD 20892 USA

[2] NICHHD, Cell Biol & Metab Branch, Bethesda, MD 20892 USA

来源：

GENES & DEVELOPMENT | 2006年 / 20卷 / 17期

关键词：

Hfq; OmpC; OmpA; sigma(E); OmpR;

D O I：

10.1101/gad.1457506

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

MicF, one of the first chromosomally encoded regulatory small RNAs (sRNAs) to be discovered, was found to modulate the expression of OmpF, an abundant outer membrane protein. Several recent papers have now shown that this is not an isolated case. At least five other sRNAs also regulate the synthesis of outer membrane porins, and additional sRNAs modulate the expression of other outer membrane proteins. Here we review what is known about these sRNAs and discuss the implications of this regulation.

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收藏

页码：2338 / 2348

页数：11

相关论文

共 62 条

[11] A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome [J].

Chen, S ;

Lesnik, EA ;

Hall, TA ;

Sampath, R ;

Griffey, RH ;

Ecker, DJ ;

Blyn, LB .

BIOSYSTEMS, 2002, 65 (2-3) :157-177

[12] POSTTRANSCRIPTIONAL REPRESSION OF ESCHERICHIA-COLI OMPF PROTEIN IN RESPONSE TO REDOX STRESS - POSITIVE CONTROL OF THE MICF ANTISENSE RNA BY THE SOXRS LOCUS [J].

CHOU, JH ;

GREENBERG, JT ;

DEMPLE, B .

JOURNAL OF BACTERIOLOGY, 1993, 175 (04) :1026-1031

[13] MARA LOCUS CAUSES DECREASED EXPRESSION OF OMPF PORIN IN MULTIPLE-ANTIBIOTIC-RESISTANT (MAR) MUTANTS OF ESCHERICHIA-COLI [J].

COHEN, SP ;

MCMURRY, LM ;

LEVY, SB .

JOURNAL OF BACTERIOLOGY, 1988, 170 (12) :5416-5422

[14] MicF:: An antisense RNA gene involved in response of Escherichia coli to global stress factors [J].

Delihas, N ;

Forst, S .

JOURNAL OF MOLECULAR BIOLOGY, 2001, 313 (01) :1-12

[15] Down-regulation of porins by a small RNA bypasses the essentiality of the regulated intramembrane proteolysis protease RseP in Escherichia coli [J].

Douchin, V ;

Bohn, C ;

Bouloc, P .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (18) :12253-12259

[16] THE OMPA 5' UNTRANSLATED RNA SEGMENT FUNCTIONS IN ESCHERICHIA-COLI AS A GROWTH-RATE-REGULATED MESSENGER-RNA STABILIZER WHOSE ACTIVITY IS UNRELATED TO TRANSLATIONAL EFFICIENCY [J].

EMORY, SA ;

BELASCO, JG .

JOURNAL OF BACTERIOLOGY, 1990, 172 (08) :4472-4481

[17] SPECIFIC REGIONS OF ESCHERICHIA-COLI OMPF PROTEIN INVOLVED IN ANTIGENIC AND COLICIN RECEPTOR-SITES AND IN STABLE TRIMERIZATION [J].

FOUREL, D ;

MIZUSHIMA, S ;

BERNADAC, A ;

PAGES, JM .

JOURNAL OF BACTERIOLOGY, 1993, 175 (09) :2754-2757

[18] The small RNA regulators of Escherichia coli:: Roles and mechanisms [J].

Gottesman, S .

ANNUAL REVIEW OF MICROBIOLOGY, 2004, 58 :303-328

[19] Remodelling of the Escherichia coli outer membrane by two small regulatory RNAs [J].

Guillier, M ;

Gottesman, S .

MOLECULAR MICROBIOLOGY, 2006, 59 (01) :231-247

[20]

HANTKE K, 1997, METAL IONS GENE REGU, P11

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