On the acylation reactions of aza-allyl carbanions derived from N-[bis(methylthio)methylene]glycine ethyl ester and N-[bis(methylthio)methylene] benzylamine

被引：3

作者：

AlvarezIbarra, C

Csaky, AG

MartinezSantos, E

Quiroga, ML

机构：

[1] Depto. de Quimica Orgánica, Universidad Complutense, Ciudad Universitaria, s/n

来源：

TETRAHEDRON | 1997年 / 53卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(97)00091-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New aspects of the acylation reaction of the aza-allyl anions derived from 1 and 2 have been studied. Under suitable reaction conditions, oxazoles 5, alpha,alpha-disubstituted alpha-acyl-alpha-amino acid derivatives 3, and alpha,beta-didehydroamino acid derivatives 7 can be prepared. A new 1,3-diamino-2-propanol derivative 8 was isolated by reaction of the C-acyl intermediate derived from N-[bis(methylthio)methylene]- benzylamine 2 and the anion 2 through an in situ addition-cyclocondensation tandem reaction. (C) 1997 Elsevier Science Ltd.

引用

页码：3679 / 3692

页数：14

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