Metabolic assessment - a key to nutritional strategies for health

被引:11
作者
German, JB [1 ]
Watkins, SM
机构
[1] Univ Calif Davis, Dept Food Sci & Technol, Davis, CA 95616 USA
[2] Nestle Res Ctr, CH-100 Lausanne, Switzerland
[3] Lipomice Technol Inc, W Sacramento, CA 95691 USA
关键词
D O I
10.1016/j.tifs.2004.01.009
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
With the success following the establishment of essential nutrients and the practical elimination of deficiency diseases through fortification of the food supply, nutrition is now turning to a new generation of issues-promoting health, preventing disease, and assuring individual balanced food intake. Nutritional strategies to improve health must now focus on variations among individuals in their metabolic response to nutrients. What works for one individual does not necessarily work for all individuals. Hence, assessments that reflect global metabolism within individuals must be developed. Assessment of health can be documented by direct measurements and nutritional guidance to provide multiple health benefits to individuals. The quantitative measurement of all fatty acids in blood is an example of how metabolomic approaches will proceed in the future. (C) 2004 Published by Elsevier Ltd.
引用
收藏
页码:541 / 549
页数:9
相关论文
共 58 条
[11]  
1744::AID-JSFA725&gt
[12]  
3.0.CO
[13]  
2-W
[14]   Functional genomics [J].
Fields, S ;
Kohara, Y ;
Lockhart, DJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (16) :8825-8826
[15]   INHIBITION OF OXIDATION OF HUMAN LOW-DENSITY-LIPOPROTEIN BY PHENOLIC SUBSTANCES IN RED WINE [J].
FRANKEL, EN ;
KANNER, J ;
GERMAN, JB ;
PARKS, E ;
KINSELLA, JE .
LANCET, 1993, 341 (8843) :454-457
[16]   The development of functional foods: lessons from the gut [J].
German, B ;
Schiffrin, EJ ;
Reniero, R ;
Mollet, B ;
Pfeifer, A ;
Neeser, JR .
TRENDS IN BIOTECHNOLOGY, 1999, 17 (12) :492-499
[17]   The health benefits of wine [J].
German, JB ;
Walzem, RL .
ANNUAL REVIEW OF NUTRITION, 2000, 20 :561-593
[18]   Decrease in phosphocreatine level in skeletal muscle of SIV-infected rhesus macaques correlates with decrease in intracellular glutathione [J].
Hack, V ;
Gross, A ;
Bohme, A ;
StahlHennig, C ;
Droge, W .
AIDS RESEARCH AND HUMAN RETROVIRUSES, 1997, 13 (13) :1089-1091
[19]   A RATIONALE FOR PLASMA-CHOLESTEROL MODULATION BY DIETARY FATTY-ACIDS - MODELING THE HUMAN RESPONSE IN ANIMALS [J].
HAYES, KC ;
PRONCZUK, A ;
KHOSLA, P .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 1995, 6 (04) :188-194
[20]   Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides - The European Atherosclerosis Research Study (EARS) [J].
Humphries, SE ;
Nicaud, V ;
Margalef, J ;
Tiret, L ;
Talmud, PJ .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1998, 18 (04) :526-534