Carbapenemase-Producing Enterobacteriaceae in Spain in 2012

被引：111

作者：

Oteo, Jesus ^{[1
]}

Saez, David ^{[1
]}

Bautista, Veronica ^{[1
]}

Fernandez-Romero, Sara ^{[1
]}

Manuel Hernandez-Molina, Juan ^{[2
]}

Perez-Vazquez, Maria ^{[1
]}

Aracil, Belen ^{[1
]}

Campos, Jose ^{[1
,3
]}

机构：

[1] Ctr Nacl Microbiol Virol & Inmunol Sanitarias Maja, Dept Bacteriol, Antibiot Lab, Madrid, Spain

[2] Hosp Univ Carlos Haya, Dept Microbiol, Malaga, Spain

[3] CSIC, Madrid, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 12期

关键词：

OXA-48-PRODUCING KLEBSIELLA-PNEUMONIAE; BETA-LACTAMASE; OUTBREAK; EPIDEMIOLOGY; HOSPITALS; EMERGENCE; SPREAD;

D O I：

10.1128/AAC.01513-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1. Interhospital spread of carbapenemase-producing Klebsiella pneumoniae was due to a limited number of multilocus sequence types (MLST) and carbapenemase types, including ST15-VIM-1, ST11-OXA-48, ST405-OXA-48, ST101-KPC-2, and ST11-VIM-1. The number of CPE cases in Spain has increased sharply in recent years, due mainly to the emergence of OXA-48.

引用

页码：6344 / 6347

页数：4

共 17 条

[1]

[Anonymous], 2013, EURO SURVEILL

[2]

Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe [J].

Canton, R. ;

Akova, M. ;

Carmeli, Y. ;

Giske, C. G. ;

Glupczynski, Y. ;

Gniadkowski, M. ;

Livermore, D. M. ;

Miriagou, V. ;

Naas, T. ;

Rossolini, G. M. ;

Samuelsen, O. ;

Seifert, H. ;

Woodford, N. ;

Nordmann, P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (05) :413-431

[3]

*EUR COMM ANT SUSC, 2013, CLIN BREAKP

[4]

Rapid emergence and spread of OXA-48-producing carbapenem-resistant Enterobacteriaceae isolates in Belgian hospitals [J].

Glupczynski, Youri ;

Huang, Te-Din ;

Bouchahrouf, Warda ;

de Castro, Roberta Rezende ;

Bauraing, Caroline ;

Gerard, Michele ;

Verbruggen, Anne-Marie ;

Deplano, Ariane ;

Denis, Olivier ;

Bogaerts, Pierre .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2012, 39 (02) :168-172

[5]

Prevalence and molecular epidemiology of acquired AmpC β-lactamases and carbapenemases in Enterobacteriaceae isolates from 35 hospitals in Spain [J].

Miro, E. ;

Agueero, J. ;

Larrosa, M. N. ;

Fernandez, A. ;

Conejo, M. C. ;

Bou, G. ;

Gonzalez-Lopez, J. J. ;

Lara, N. ;

Martinez-Martinez, L. ;

Oliver, A. ;

Aracil, B. ;

Oteo, J. ;

Pascual, A. ;

Rodriguez-Bano, J. ;

Zamorano, L. ;

Navarro, F. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2013, 32 (02) :253-259

[6]

Carbapenem resistance in Enterobacteriaceae: here is the storm! [J].

Nordmann, Patrice ;

Dortet, Laurent ;

Poirel, Laurent .

TRENDS IN MOLECULAR MEDICINE, 2012, 18 (05) :263-272

[7]

Emergence of OXA-48-producing Klebsiella pneumoniae and the novel carbapenemases OXA-244 and OXA-245 in Spain [J].

Oteo, Jesus ;

Manuel Hernandez, Juan ;

Espasa, Mateu ;

Fleites, Ana ;

Saez, David ;

Bautista, Veronica ;

Perez-Vazquez, Maria ;

Dolores Fernandez-Garcia, Ma ;

Delgado-Iribarren, Alberto ;

Sanchez-Romero, Isabel ;

Garcia-Picazo, Luisa ;

Dolores Miguel, Ma ;

Solis, Sonia ;

Aznar, Esteban ;

Trujillo, Gloria ;

Mediavilla, Concepcion ;

Fontanals, Dionisia ;

Rojo, Susana ;

Vindel, Ana ;

Campos, Jose .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (02) :317-321

[8]

Abdominal abscess due to NDM-1-producing Klebsiella pneumoniae in Spain [J].

Oteo, Jesus ;

Domingo-Garcia, Diego ;

Fernandez-Romero, Sara ;

Saez, David ;

Guiu, Alba ;

Cuevas, Oscar ;

Lopez-Brea, Manuel ;

Campos, Jose .

JOURNAL OF MEDICAL MICROBIOLOGY, 2012, 61 (06) :864-867

[9]

OUTBREAK OF VIM-1-CARBAPENEMASE-PRODUCING ENTEROBACTER CLOACAE IN A PEDIATRIC INTENSIVE CARE UNIT [J].

Oteo, Jesus ;

Luis Hernandez-Almaraz, Jose ;

Gil-Anton, Javier ;

Vindel, Ana ;

Fernandez, Sara ;

Bautista, Veronica ;

Campos, Jose .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (12) :1144-1146

[10]

Infections caused by OXA-48-producing Klebsiella pneumoniae in a tertiary hospital in Spain in the setting of a prolonged, hospital-wide outbreak [J].

Ramon Pano-Pardo, Jose ;

Ruiz-Carrascoso, Guillermo ;

Navarro-San Francisco, Carolina ;

Gomez-Gil, Rosa ;

Mora-Rillo, Marta ;

Pilar Romero-Gomez, Maria ;

Fernandez-Romero, Natalia ;

Garcia-Rodriguez, Julio ;

Perez-Blanco, Veronica ;

Moreno-Ramos, Francisco ;

Mingorance, Jesus .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (01) :89-96

← 1 2 →