An apertureless near-field microscope for fluorescence imaging

被引:83
作者
Yang, TJ [1 ]
Lessard, GA [1 ]
Quake, SR [1 ]
机构
[1] CALTECH, Dept Appl Phys, Pasadena, CA 91125 USA
关键词
D O I
10.1063/1.125759
中图分类号
O59 [应用物理学];
学科分类号
摘要
We describe an apertureless near field microscope for imaging fluorescent samples. Optical contrast is generated by exploiting fluorescent quenching near a metallized atomic force microscope tip. This microscope has been used to image fluorescent latex beads with subdiffraction limit resolution. The use of fluorescence allows us to prove that the contrast mechanism is indeed spectroscopic in origin. (C) 2000 American Institute of Physics. [S0003-6951(00)00403-4].
引用
收藏
页码:378 / 380
页数:3
相关论文
共 18 条
[1]   NEAR-FIELD OPTICAL MICROSCOPY BY LOCAL PERTURBATION OF A DIFFRACTION SPOT [J].
BACHELOT, R ;
GLEYZES, P ;
BOCCARA, AC .
MICROSCOPY MICROANALYSIS MICROSTRUCTURES, 1994, 5 (4-6) :389-397
[2]  
Chance R. R., 1978, ADV CHEM PHYS, V37, P1, DOI DOI 10.1002/9780470142561.CH1
[3]   Nanotubes as nanoprobes in scanning probe microscopy [J].
Dai, HJ ;
Hafner, JH ;
Rinzler, AG ;
Colbert, DT ;
Smalley, RE .
NATURE, 1996, 384 (6605) :147-150
[4]   Photoluminescence spectroscopy of single CdSe nanocrystallite quantum dots [J].
Empedocles, SA ;
Norris, DJ ;
Bawendi, MG .
PHYSICAL REVIEW LETTERS, 1996, 77 (18) :3873-3876
[5]  
HAROOTUNIAN A, 1984, J OPT SOC AM A, V1, P1293
[6]   Facts and artifacts in near-field optical microscopy [J].
Hecht, B ;
Bielefeldt, H ;
Inouye, Y ;
Pohl, DW ;
Novotny, L .
JOURNAL OF APPLIED PHYSICS, 1997, 81 (06) :2492-2498
[7]   NEAR-FIELD SPECTROSCOPY OF THE QUANTUM CONSTITUENTS OF A LUMINESCENT SYSTEM [J].
HESS, HF ;
BETZIG, E ;
HARRIS, TD ;
PFEIFFER, LN ;
WEST, KW .
SCIENCE, 1994, 264 (5166) :1740-1745
[8]   NEAR-FIELD SCANNING OPTICAL MICROSCOPE WITH A METALLIC PROBE TIP [J].
INOUYE, Y ;
KAWATA, S .
OPTICS LETTERS, 1994, 19 (03) :159-161
[9]   Feasibility of molecular-resolution fluorescence near-field microscopy using multi-photon absorption and field enhancement near a sharp tip [J].
Kawata, Y ;
Xu, C ;
Denk, W .
JOURNAL OF APPLIED PHYSICS, 1999, 85 (03) :1294-1301
[10]   Near-field probing of vibrational absorption for chemical microscopy [J].
Knoll, B ;
Keilmann, F .
NATURE, 1999, 399 (6732) :134-137