Five-year survival after intensive care - Comparison of 12,180 patients with the general population

Objectives: A) To examine the long-term survival of critically ill patients compared with the general population in a nationwide sample of patients requiring intensive care; and b) to analyze long term survival stratified by specific diagnostic subgroups, Design: Prospective, inception cohort study, Setting: Twenty five Finnish intensive care units (ICUs) at 17 hospitals, including 13 ICUs in five tertiary care centers, Patients: A consecutive sample of 12,180 adult patients who were admitted to ICUs in 1987, The sample was further divided into seven diagnostic subgroups, Interventions: None, Measurements and Main Results: Vital status at 5 yrs after admission to an ICU was examined and compared to the age- and gender-adjusted survival of Finland's general population, Among ICU patients, the 5-yr mortality rate was 3.3 times that of Finland's general population (95% confidence interval 3.0 to 3.4). At 2 yrs, the survival rate paralleled that of the general population, At 5 yrs, the relative survival rate of the ICU patients was 66.7%, Cancer was a strong determinant of a poor outcome in multivariate analysis (relative risk 3.17; 95% confidence interval 2.86 to 3.51), The 5-yr mortality rate of the ICU patients compared with the general population was highest among patients admitted to the ICU after intoxication, Trauma victims and patients admitted to the ICU with a cardiovascular diagnosis reached the risk of death of the general population in the shortest time, Conclusions: ICU patients reached a life expectancy similar to the general population, on average, 2 yrs after admission, The time after which the survival parallels that of the general population depends, however, on the diagnostic category.