Regio- and Stereoselective Isomerizations of Allenamides: Synthesis of 2-Amido-Dienes and Their Tandem Isomerization-Electrocyclic Ring-Closure

被引：56

作者：

Hayashi, Ryuji

Hsung, Richard P. ^{[1
]}

Feltenberger, John B.

Lohse, Andrew G.

机构：

[1] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 10期

关键词：

DIELS-ALDER REACTIONS; STEREOCHEMICAL ASSIGNMENT; COPPER; ESTERS; 2-AMINO-1,3-BUTADIENES; 1,3,5-HEXATRIENES; AMIDATION; CATALYSTS; HALIDES; DIENES;

D O I：

10.1021/ol900647s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A regio- and stereoselective isomerization of allenamides is described, leading to preparations of de novo 2-amido-dienes and a tandem isomerization-6 pi-electron electrocyclic ring-closure.

引用

页码：2125 / 2128

页数：4

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