A novel regio- and stereoselective synthesis of isoindolines

被引：24

作者：

Kukkola, PJ

Bilci, NA

Ikeler, TJ

机构：

[1] Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 29期

关键词：

D O I：

10.1016/0040-4039(96)01018-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The described synthesis of isomeric isoindoline dicarboxylic acid analogs 1 and 2, two potent ETA selective receptor antagonists, involves an efficient regioselective route to highly functionalized dibenzoylbenzenes and a novel methodology for the stereoselective preparation of trans and cis 1,3-disubstituted isoindolines. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5065 / 5068

页数：4

共 18 条

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