Structure of the histone-like protein H-NS and its role in regulation and genome superstructure

被引:137
作者
Rimsky, S [1 ]
机构
[1] Univ Paris 11, Ecole Normale Super Cachan, LBPA, CNRS,UMR 8113, F-94235 Cachan, France
关键词
D O I
10.1016/j.mib.2004.02.001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
H-NS belongs to the group of histone-like proteins in Gram-negative bacteria and is also a pleiotropic regulator of genes implicated in many responses to environmental changes. It plays a dual role in structuring DNA and in regulating transcription. Recent advances have been made in elucidating the structure and oligomerisation properties of this protein, thus aiding in the understanding of the molecular relationship between its two major functions.
引用
收藏
页码:109 / 114
页数:6
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