Novel synthesis of fused isoxazolidines via a palladium catalysed allene insertion-intramolecular 1,3-dipolar cycloaddition cascade reaction

被引：28

作者：

Aftab, T

Grigg, R ^{[1
]}

Ladlow, M

Sridharan, V

Thornton-Pett, M

机构：

[1] Univ Leeds, Sch Chem, MIDAS Ctr, Leeds LS2 9JT, W Yorkshire, England

[2] GlaxoSmithkline, Cambridge Chem Unit, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 16期

关键词：

D O I：

10.1039/b205069b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A one pot, three component palladium catalysed allenation of aryl iodides, in combination with a nitrone cycloaddition, leads to formation of fused isoxazolidines, creating two rings, two stereocentres and one tetrasubstituted carbon centre.

引用

页码：1754 / 1755

页数：2

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