Enamines in solid-phase:: synthesis and reactivity towards electrophiles

被引：10

作者：

Aznar, F ^{[1
]}

Valdés, C ^{[1
]}

Cabal, MP ^{[1
]}

机构：

[1] Univ Oviedo, Inst Quim Organomet Enrique Moles, Unidad Asociada, CSIC, E-33071 Oviedo, Spain

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(00)00946-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enamines are synthesized in solid-phase by amination of terminal acetylenes with a secondary amine attached to Wang resin in a process catalyzed by mercury(II) acetate. The enamines obtained react with electrophiles such as isocyanates and nitroolefins to give rise to the expected addition products, which can be released from the resin by hydrolysis of the enamine under mild acidic conditions. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：5683 / 5687

页数：5

共 13 条

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