Similarities in features of autism and asthma and a possible link to acetaminophen use

被引：46

作者：

Becker, Kevin G. ^{[1
]}

Schultz, Stephen T. ^{[2
]}

机构：

[1] NIA, Biomed Res Ctr, NIH, Gene Express & Genom Unit, Baltimore, MD 21224 USA

[2] Rosalind Franklin Univ Med & Sci, Chicago Med Sch, N Chicago, IL 60064 USA

来源：

MEDICAL HYPOTHESES | 2010年 / 74卷 / 01期

基金：

美国国家卫生研究院;

关键词：

MIGRATION INHIBITORY FACTOR; IMMUNE-RESPONSE; PARACETAMOL USE; GENETIC POLYMORPHISMS; SPECTRUM DISORDER; FACTOR MIF; CHILDREN; RISK; PREVALENCE; BRAIN;

D O I：

10.1016/j.mehy.2009.08.033

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Autism and autism spectrum disorders are enigmatic conditions that have their origins in the interaction of genes and environmental factors. In this hypothesis, genes statistically associated with autism are emphasized to be important in inflammation and in innate immune pathways, including pathways for susceptibility to asthma. The role of acetaminophen (paracetamol) in an increased risk for asthma is described and a possible similar link to an increased risk for autism is suggested. (C) Published by Elsevier Ltd.

引用

页码：7 / 11

页数：5

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