GdIII-functionalized fluorescent quantum dots as multimodal imaging probes

被引:120
作者
Yang, Heesun [1 ]
Santra, Swadeshmukul
Walter, Glenn A.
Holloway, Paul H.
机构
[1] Hongik Univ, Dept Mat Sci & Engn, Seoul 121791, South Korea
[2] Univ Cent Florida, Nanosci Technol Ctr, Orlando, FL 32826 USA
[3] Univ Cent Florida, Dept Chem, Orlando, FL 32826 USA
[4] Univ Cent Florida, Biomol Sci Ctr, Orlando, FL 32826 USA
[5] Univ Florida, Dept Physiol & Funct Genom, Gainesville, FL 32610 USA
[6] Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32610 USA
关键词
MRI CONTRAST AGENTS; HIGH-RELAXIVITY; RADIO-OPAQUE; CDS; NANOPARTICLES; DELINEATION; EXCHANGE;
D O I
10.1002/adma.200502665
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Multimodal probes of Gd-III-functionalized silica-coated CdS:Mn/ZnS quantum dots (see figure) that exhibit yellow fluorescence and strong paramagnetism are reported. High magnetic resonance imaging (MRI) contrast is exhibited by these quantum dots. These properties make for a probe that can operate in multiple modes, which is highly desirable for in vivo bioimaging applications.
引用
收藏
页码:2890 / +
页数:6
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