Cutaneous innervation in chronic inflammatory demyelinating polyneuropathy

被引:75
作者
Chiang, MC
Lin, YH
Pan, CL
Tseng, TJ
Lin, WM
Hsieh, ST
机构
[1] Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan
关键词
D O I
10.1212/WNL.59.7.1094
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors evaluated epidermal nerve density (END) and thermal thresholds in 18 patients with chronic inflammatory demyelinating polyneuropathy (CIDP). END of patients with CIDP were lower than those of controls (4.5 +/- 2.9 vs 10.5 +/- 3.9 fibers/mm, P < 0.001). Reduced END were associated with autonomic symptoms. Thermal thresholds of patients with CIDP were elevated (88.2% for warm stimuli and 70.6% for cold stimuli). Patients with CIDP have small-fiber sensory and autonomic neuropathies.
引用
收藏
页码:1094 / 1098
页数:5
相关论文
共 10 条
[1]   Density of sympathetic axons in sural nerve biopsies of neuropathy patients is related to painfulness [J].
Bickel, A ;
Butz, M ;
Schmelz, M ;
Handwerker, HO ;
Neundörfer, B .
PAIN, 2000, 84 (2-3) :413-419
[2]  
CORNBLATH DR, 1991, NEUROLOGY, V41, P617
[3]   UNMYELINATED FIBERS IN SURAL NERVE BIOPSIES OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY [J].
GIBBELS, E ;
KENTENICH, M .
ACTA NEUROPATHOLOGICA, 1990, 80 (04) :439-447
[4]   Intraepidermal nerve fiber density in patients with painful sensory neuropathy [J].
Holland, NR ;
Stocks, A ;
Hauer, P ;
Cornblath, DR ;
Griffin, JW ;
McArthur, JC .
NEUROLOGY, 1997, 48 (03) :708-711
[5]   Pathology of nerve terminal degeneration in the skin [J].
Hsieh, ST ;
Chiang, HY ;
Lin, WM .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2000, 59 (04) :297-307
[6]   THE INNERVATION OF HUMAN EPIDERMIS [J].
KENNEDY, WR ;
WENDELSCHAFERCRABB, G .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1993, 115 (02) :184-190
[7]   Autonomic impairment in painful neuropathy [J].
Novak, V ;
Freimer, ML ;
Kissel, JT ;
Sahenk, Z ;
Periquet, IM ;
Nash, SM ;
Collins, MP ;
Mendell, JR .
NEUROLOGY, 2001, 56 (07) :861-868
[8]   Degeneration of nociceptive nerve terminals in human peripheral neuropathy [J].
Pan, CL ;
Lin, YH ;
Lin, WM ;
Tai, TY ;
Hsieh, ST .
NEUROREPORT, 2001, 12 (04) :787-792
[9]   Complex Regional Pain Syndrome I (CRPS I): Prospective study and laboratory evaluation [J].
Sandroni, P ;
Low, PA ;
Ferrer, T ;
Opfer-Gehrking, TL ;
Willner, CL ;
Wilson, PR .
CLINICAL JOURNAL OF PAIN, 1998, 14 (04) :282-289
[10]   THERMAL TESTING - NORMATIVE DATA AND REPEATABILITY FOR VARIOUS TEST ALGORITHMS [J].
YARNITSKY, D ;
SPRECHER, E .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1994, 125 (01) :39-45