In and out of the replication factory

被引:19
作者
Meister, Peter
Taddei, Angela
Gasser, Susan M.
机构
[1] Friedrich Miescher Inst Biomed Res, CH-4058 Basel, Switzerland
[2] Inst Curie, UMR 218, Sect Rech, F-75231 Paris, France
关键词
D O I
10.1016/j.cell.2006.06.014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Cell, Kitamura et al. (2006) use live-fluorescence microscopy to monitor individual genomic loci as they replicate in budding yeast. They confirm that DNA is recruited to replication factories and show that sister replication forks initiated from the same origin are held together within a single replication factory.
引用
收藏
页码:1233 / 1235
页数:3
相关论文
共 8 条
[1]   Molecular biology - The organization of replication and transcription [J].
Cook, PR .
SCIENCE, 1999, 284 (5421) :1790-1795
[2]   Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells [J].
Jackson, DA ;
Pombo, A .
JOURNAL OF CELL BIOLOGY, 1998, 140 (06) :1285-1295
[3]   The extrusion-capture model for chromosome partitioning in bacteria [J].
Lemon, KP ;
Grossman, AD .
GENES & DEVELOPMENT, 2001, 15 (16) :2031-2041
[4]   Monitoring S phase progression globally and locally using BrdU incorporation in TK+ yeast strains [J].
Lengronne, A ;
Pasero, P ;
Bensimon, A ;
Schwob, E .
NUCLEIC ACIDS RESEARCH, 2001, 29 (07) :1433-1442
[5]   Epigenomic replication: linking epigenetics to DNA replication [J].
McNairn, AJ ;
Gilbert, DM .
BIOESSAYS, 2003, 25 (07) :647-656
[6]   FIXED SITE OF DNA-REPLICATION IN EUKARYOTIC CELLS [J].
PARDOLL, DM ;
VOGELSTEIN, B ;
COFFEY, DS .
CELL, 1980, 19 (02) :527-536
[7]   Replication dynamics of the yeast genome [J].
Raghuraman, MK ;
Winzeler, EA ;
Collingwood, D ;
Hunt, S ;
Wodicka, L ;
Conway, A ;
Lockhart, DJ ;
Davis, RW ;
Brewer, BJ ;
Fangman, WL .
SCIENCE, 2001, 294 (5540) :115-121
[8]  
TUBO RA, 1987, J BIOL CHEM, V262, P5857