Novel acetoxylation and C-C coupling reactions at unactivated positions in α-amino acid derivatives

被引：473

作者：

Reddy, B. V. Subba ^{[1
]}

Reddy, Leleti Rajender ^{[1
]}

Corey, E. J. ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 15期

关键词：

ASYMMETRIC-SYNTHESIS; H BONDS; ENANTIOSELECTIVE SYNTHESIS; METHYL-GROUPS; L-THREONINE; OXIDATION; ESTERS;

D O I：

10.1021/ol061389j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under special conditions, N-phthaloyl-alpha-amino acid amides of 8-aminoquinoline can be either acetoxylated or arylated selectively at the ss-carbon. In certain cases, arylation can be effected at the gamma-carbon.

引用

页码：3391 / 3394

页数：4

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