Isotsaokoin, an antifungal agent from Amomum tsao-ko

被引：48

作者：

Moon, SS ^{[1
]}

Lee, JY ^{[1
]}

Cho, SC ^{[1
]}

机构：

[1] Kongju Natl Univ, Dept Chem, Kong Ju 314701, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 05期

关键词：

D O I：

10.1021/np030464l

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bioassay-guided purification of a methanol extract from Amomum tsao-ko led to the isolation of the bicyclic nonane isotsaokoin (1) as the major active principle, an isomer of the previously reported tsaokoin (2). The stereochemical relationship of 1 and 2 was investigated by NOE experiments and Mosher ester derivatization. Compound 1 showed antifungal activity against Trycophyton mentagrophytes.

引用

页码：889 / 891

页数：3

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