Intermolecular rhodium-catalyzed carbometalation/Heck-type reaction in water

被引：61

作者：

Kurahashi, Takuya ^{[1
]}

Shinokubo, Hiroshi ^{[1
]}

Osuka, Atsuhiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 38期

关键词：

alkynes; aqueous media; boron; domino reactions; rhodium;

D O I：

10.1002/anie.200602585

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Only in water: A fully intermolecular rhodium-catalyzed domino coupling reaction, in which aryl boronic acids react with alkynes and acrylates to afford substituted 1,3-dienes, can only be successfully carried out in water. The reaction predominantly provides 1,4-addition products in aqueous THF and Heck-type addition products in a homogenized system with sodium decyl sulfate. cod = 1,5-cyclooctadiene. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6336 / 6338

页数：3

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