Amine-catalyzed addition of azide ion to α,β-unsaturated carbonyl compounds

被引：83

作者：

Guerin, DJ ^{[1
]}

Horstmann, TE ^{[1
]}

Miller, SJ ^{[1
]}

机构：

[1] Boston Coll, Dept Chem, Merkert Chem Ctr, Chestnut Hill, MA 02467 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 07期

关键词：

D O I：

10.1021/ol9909076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new protocol for the beta-azidation of alpha,beta-unsaturated carbonyl compounds is described, The method employs tertiary amines as catalysts for azide addition. The azide source is a 1:1 mixture of TMSN3 and AcOH. Tertiary amines, either in solution or bound to a solid support, are efficient catalysts for the reaction.

引用

页码：1107 / 1109

页数：3

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