New cytotoxic alkyl phloroglucinols from Protorhus thouvenotii

被引：14

作者：

Cao, SG

Schilling, JK

Randrianasolo, A

Andriantsiferana, R

Rasamison, VE

Kingston, DGI ^{[1
]}

机构：

[1] Virginia Polytech Inst & State Univ, Dept Chem MC 0212, Blacksburg, VA 24061 USA

[2] Missouri Bot Garden, St Louis, MO 63166 USA

[3] Ctr Natl Applicat & Rech Pharmaceut, Antananarivo, Madagascar

来源：

PLANTA MEDICA | 2004年 / 70卷 / 07期

关键词：

D O I：

10.1055/s-2004-827195

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Two new cytotoxic alkylene phloroglucinols and one known compound were isolated through chromatographic separation from the methanolic extract of the dried fruits of Protorhus thouvenotii (Anacardiaceae). The compounds showed marginal in vitro cytotoxicity in the A2780 ovarian cancer cell line assay with an IC50 Of 11 mug/mL.

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收藏

页码：683 / 685

页数：3

相关论文

共 14 条

[1]

ALKYL AND ALKENYL RESORCINOLS FROM AN AUSTRALIAN MARINE SPONGE, HALICLONA SP (HAPLOSCLERIDA, HALICLONIDAE) [J].

BARROW, RA ;

CAPON, RJ .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1991, 44 (10) :1393-1405

[2]

New cytotoxic terpenoids from the wood of Vepris punctata from the Madagascar rainforest [J].

Chaturvedula, VSP ;

Schilling, JK ;

Miller, JS ;

Andriantsiferana, R ;

Rasamison, VE ;

Kingston, DGI .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (05) :895-898

[3]

5-(12-HEPTADECENYL)-RESORCINOL, THE MAJOR COMPONENT OF THE ANTIFUNGAL ACTIVITY IN THE PEEL OF MANGO FRUIT [J].

COJOCARU, M ;

DROBY, S ;

GLOTTER, E ;

GOLDMAN, A ;

GOTTLIEB, HE ;

JACOBY, B ;

PRUSKY, D .

PHYTOCHEMISTRY, 1986, 25 (05) :1093-1095

[4]

ANTIBACTERIAL AND MOLLUSCICIDAL PHENOLIC-ACIDS FROM SPONDIAS MOMBIN [J].

CORTHOUT, J ;

PIETERS, L ;

CLAEYS, M ;

GEERTS, S ;

VANDENBERGHE, D ;

VLIETINCK, A .

PLANTA MEDICA, 1994, 60 (05) :460-463

[5]

Cardanols from leaves of Rhus thyrsiflora [J].

Franke, K ;

Masaoud, M ;

Schmidt, J .

PLANTA MEDICA, 2001, 67 (05) :477-479

[6]

GAMBARO V, 1986, PLANTA MED, V52, P20

[7]

Isolation of gallic acid esters as antiplasmodial constituents of Swintonia foxworthyi (Anacardiaceae) [J].

Horgen, FD ;

Madulid, DA ;

Angerhofer, CK ;

Pezzuto, JM ;

Soejarto, DD ;

Farnsworth, NR .

PHYTOMEDICINE, 1997, 4 (04) :353-356

[8]

2-hydroxy-4-methoxybenzaldehyde: A potent tyrosinase inhibitor from African medicinal plants [J].

Kubo, I ;

Kinst-Hori, I .

PLANTA MEDICA, 1999, 65 (01) :19-22

[9]

Process for isolation of cardanol from technical cashew (Anacardium occidentale L.) nut shell liquid [J].

Kumar, PP ;

Paramashivappa, R ;

Vithayathil, PJ ;

Rao, PVS ;

Rao, AS .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (16) :4705-4708

[10]

6-PENTADECYLSALICYLIC ACID - AN ANTITHROMBIN COMPONENT ISOLATED FROM THE STEM OF RHUS-SEMIALATA VAR ROXBURGHII [J].

KUO, SC ;

TENG, CM ;

LEE, LG ;

CHIU, TH ;

WU, TS ;

HUANG, SC ;

WU, JB ;

SHIEH, TY ;

CHANG, RJ ;

CHOU, TC .

PLANTA MEDICA, 1991, 57 (03) :247-249