Enantioselective reduction of heteroaromatic β,γ-unsaturated ketones as an alternative to allylboration of aldehydes.: Application:: asymmetric synthesis of SIB-1508Y

被引：27

作者：

Felpin, FX ^{[1
]}

Bertrand, MJ ^{[1
]}

Lebreton, J ^{[1
]}

机构：

[1] Fac Sci & Tech, Synth Organ Lab, CNRS, UMR 6513, F-44322 Nantes 3, France

来源：

TETRAHEDRON | 2002年 / 58卷 / 37期

关键词：

allylboration; enantioselective reduction; ketone; SIB-1508Y;

D O I：

10.1016/S0040-4020(02)00819-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective reduction of heteroaromatic beta,gamma-unsaturated ketones was found to be an efficient and convenient alternative to the allylboration of corresponding aldehydes. This new method was used for the formal asymmetric synthesis of SIB-1508Y 2. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：7381 / 7389

页数：9

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