Weakly Coordinating Directing Groups for Ruthenium(II)-Catalyzed C-H Activation

被引：676

作者：

De Sarkar, Suman ^{[1
]}

Liu, Weiping ^{[1
]}

Kozhushkov, Sergei I. ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 07期

基金：

欧洲研究理事会;

关键词：

C-H activation; directing groups; homogenous catalysis; ruthenium; weak coordination; AEROBIC OXIDATIVE CYCLIZATION; CATALYZED ORTHO-ALKENYLATION; CARBON-HYDROGEN BONDS; AROMATIC KETONES; DIRECT ARYLATIONS; REGIOSELECTIVE SYNTHESIS; BORONIC ACIDS; EASY ROUTE; H/O-H; RUTHENIUM;

D O I：

10.1002/adsc.201400110

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Synthetically useful functional groups, including ketones, amides, carbamates, carboxylic acids, aldehydes or ethers, have been identified as weakly coordinating directing groups in efficient ruthenium(II)-catalyzed CH functionalizations. This strategy set the stage for versatile CH bond olefinations, oxygenations, nitrogenations and oxidative alkyne annulations among others. Thereby, step-economical access to diversely decorated arenes and heteroarenes was provided in a sustainable fashion.

引用

页码：1461 / 1479

页数：19

共 161 条

[1] Ackermann L., 2009, ANGEW CHEM, V121, P9976, DOI DOI 10.1002/ANGE.200902996
[2] Ackermann L., 2012, HDB GREEN CHEM, P259
[3] Ackermann L, 2007, TOP ORGANOMETAL CHEM, V24, P35, DOI 10.1007/3418_2007_062
[4] Catalytic arylations with challenging substrates: From air-stable HASPO preligands to indole syntheses and C-H-bond functionalizations
Ackermann, Lutz
[J]. SYNLETT, 2007, (04) : 507 - 526
[5] Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C-H/Het-H Bond Functionalizations
Ackermann, Lutz
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 2014, 47 (02) : 281 - 295
[6] Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C-H/C-O Bond Arylations with Phenols in Water
Ackermann, Lutz
Pospech, Jola
Potukuchi, Harish Kumar
[J]. ORGANIC LETTERS, 2012, 14 (08) : 2146 - 2149
[7] Ruthenium-Catalyzed C-H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles
Ackermann, Lutz
Diers, Emelyne
Manvar, Atul
[J]. ORGANIC LETTERS, 2012, 14 (04) : 1154 - 1157
[8] Versatile Synthesis of Isocoumarins and α-Pyrones by Ruthenium-Catalyzed Oxidative C-H/O-H Bond Cleavages
Ackermann, Lutz
Pospech, Jola
Graczyk, Karolina
Rauch, Karsten
[J]. ORGANIC LETTERS, 2012, 14 (03) : 930 - 933
[9] Ruthenium-Catalyzed Oxidative C-H Alkenylations of Anilides and Benzamides in Water
Ackermann, Lutz
Wang, Lianhui
Wolfram, Ratnakancana
Lygin, Alexander V.
[J]. ORGANIC LETTERS, 2012, 14 (03) : 728 - 731
[10] Ruthenium-Catalyzed Oxidative C-H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones
Ackermann, Lutz
Pospech, Jola
[J]. ORGANIC LETTERS, 2011, 13 (16) : 4153 - 4155

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