Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

被引：62

作者：

Dahan, S

Knutton, S

Shaw, RK

Crepin, VF

Dougan, G

Frankel, G ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci & Technol, Dept Biol Sci, Ctr Mol Microbiol & Infect, London SW7 2AZ, England

[2] Univ Birmingham, Inst Child Hlth, Birmingham B15 2TT, W Midlands, England

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 09期

关键词：

D O I：

10.1128/IAI.72.9.5452-5459.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

引用

页码：5452 / 5459

页数：8

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