The need for a standardized definition for cachexia in chronic illness

被引：48

作者：

Springer, Jochen

von Haehling, Stephan

Anker, Stefan D.

机构：

[1] Charite Berlin, Dept Cardiol, Div Appl Cachexia Res, D-13353 Berlin, Germany

[2] Charite, Div Appl Cachexia Res, Anim Res Unit, Berlin, Germany

来源：

NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM | 2006年 / 2卷 / 08期

关键词：

D O I：

10.1038/ncpendmet0247

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is no agreed definition for cachexia, and this hampers research and treatment. This Viewpoint emphasizes the importance of definitive cut-off limits for weight loss over time, and the need for straightforward diagnostic criteria. The authors suggest cut-off values for cardiac cachexia but acknowledge that the values might differ in other conditions.

引用

收藏

页码：416 / 417

页数：2

相关论文

共 11 条

[1] Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study [J].

Anker, SD ;

Negassa, A ;

Coats, AJS ;

Afzal, R ;

Poole-Wilson, PA ;

Cohn, JN ;

Yusuf, S .

LANCET, 2003, 361 (9363) :1077-1083

[2] The syndrome of cardiac cachexia [J].

Anker, SD ;

Sharma, R .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 85 (01) :51-66

[3] Wasting as independent risk factor for mortality in chronic heart failure [J].

Anker, SD ;

Ponikowski, P ;

Varney, S ;

Chua, TP ;

Clark, AL ;

WebbPeploe, KM ;

Harrington, D ;

Kox, WJ ;

PooleWilson, PA ;

Coats, AJS .

LANCET, 1997, 349 (9058) :1050-1053

[4] Therapy Insight: use of melanocortin antagonists in the treatment of cachexia in chronic disease [J].

DeBoer, Mark D. ;

Marks, Daniel L. .

NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 2006, 2 (08) :459-466

[5] Cancer cachexia [J].

Fearon, KCH ;

Moses, AGW .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 85 (01) :73-81

[6]

FREEMAN LM, 1994, NUTR REV, V52, P340, DOI 10.1111/j.1753-4887.1994.tb01358.x

[7]

INAGAKI J, 1974, CANCER-AM CANCER SOC, V33, P568, DOI 10.1002/1097-0142(197402)33:2<568::AID-CNCR2820330236>3.0.CO

[8]

2-2

[9] Pulmonary cachexia [J].

Schols, AMWJ .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 85 (01) :101-110

[10] Muscle wasting in cardiac cachexia [J].

Strassburg, S ;

Springer, J ;

Anker, SD .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2005, 37 (10) :1938-1947